Jan 13, 2020 · Men typically take alpha blockers to treat an enlarged prostate (benign prostatic hyperplasia, or BPH), which can restrict urination by putting pressure on the urethra. By relaxing the muscles in Jan 8, 2018 · The alpha-1 adrenergic receptor antagonists (also called alpha-blockers) are a family of agents that bind to and inhibit type 1 alpha-adrenergic receptors and thus inhibit smooth muscle contraction. Their major uses are for hypertension and for symptomatic benign prostatic hypertrophy. Their use in therapy of hypertension is based on the inhibition of vascular resistance in arterioles from Jul 4, 2023 · Source. Alpha-Blockers are a class of prescription medications which relax muscles around small blood vessels. By preventing the muscles from tightening, they can help improve blood flow and lower blood pressure. Their muscle relaxing properties help improve lower urinary tract symptoms in men, often caused by benign prostatic hyperplasia (BPH). Most men on alpha-blockers take them for LUTS due to BPH and do not have retention. The chances of precipitating retention due to stopping an alpha-blocker are low even when an anti-cholinergic is used. 27 , 28 Furthermore, anticholinergics have been used increasingly with and without alpha-blockers to treat LUTS, with very low rates of Jun 12, 2022 · 5-alpha reductase inhibitors can be used alone for BPH or in combination with alpha-1 blockers. 5-alpha-reductase inhibitors actually shrink the prostate and can delay the need for surgery in the future. They are not a quick fix though and can take 6-12 months to really start working. Doxazosin is in a class of medications called alpha-blockers. It relieves the symptoms of BPH by relaxing the muscles of the bladder and prostate. It lowers blood pressure by relaxing the blood vessels so that blood can flow more easily through the body. High blood pressure is a common condition and when not treated, can cause damage to the BPH medication can ease enlarged prostate symptoms, but vary in how quickly they take to work. Current options include: Alpha blockers, such as tamsulosin (Flomax), relax bladder neck muscles and muscle fibers in the prostate, resulting in increased urinary flow and decreased need to urinate. Although they effect relief within a day or two options for LUTS secondary to BPH.12-23 Doxazosin and terazosin require dose titration and blood pressure monitoring. Alpha-blockers do not alter the natural progression of BPH (little impact on prostate growth, risk of urinary retention or the need for BPH-related surgery). The most common adverse effect associated with alpha-blockers is Jun 6, 2017 · Autopsy studies in Asian and Caucasian men showed an overall prevalence of BPH in 74.8% of men. Alpha 1-adrenoceptor blockers (AB) are currently the recommended first-line therapies for benign prostatic hyperplasia (BPH) . They have high efficacy, are less expensive and have fewer adverse events (ADE) in the treatment of LUTS [1, 3, 4]. Summary. Alfuzosin (Uroxatral) is a drug that belongs to the alpha-blocker class of drugs, and is prescribed for the treatment of benign prostatic hypertrophy. The most common side are headache, dizziness, fainting, and tiredness. Drug interactions and dosage should be reviewed prior to taking this medication. vO0L.